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Concept information

Preferred term

Created: 1981-01-09T00:00:00Z

Notation: 2178

denaturation  

Definition

  • Information The process of partial or total alteration of the native structure of a macromolecule resulting from the loss of tertiary or tertiary and secondary structure that is a consequence of the disruption of stabilizing weak bonds. Denaturation can occur when proteins and nucleic acids are subjected to elevated temperature or to extremes of pH, or to non-physiological concentrations of salt, organic solvents, urea or other chemical agents.

    Created: 10/10/24

    (en)
  • Information ücre aktivitesinin bozulmasına hatta hücre ölümüne yol açacak şekilde kuvvetli asit/baz, yüksek derişimli inorganik tuz ile alkol, kloroform gibi çözgenler ya da ısı gibi fiziksel etmenlerle protein veya nükleik asitlerin işlevsel yapıda olduğu üçüncül veya ikincil yapılarının bozulması. (tr)

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URI

http://aims.fao.org/aos/agrovoc/c_2178

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