Hydrolases that specifically cleave the peptide bonds found in PROTEINS and PEPTIDES (http://www.nlm.nih.gov/cgi/mesh/2010/MB_cgi?mode=&index=10018&field=all&HM=&II=&PA=&form=&input=)
Topology is a branch of mathematics which studies properties of spaces that are invariant under any continuous deformation. Topology is used in many branches of mathematics, such as differentiable equations, dynamical systems, knot theory, and Riemann surfaces in complex analysis. (https://uwaterloo.ca/pure-mathematics/about-pure-math/what-is-pure-math/what-is-topology)